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IMPACT Study Logo - COVID-19 Immune Response Study
Research Participants for IMPACT STUDY COVID-19
Antibody Test for COVID-19

IMPACT aimed to investigate how the virus affects the immune system and how people with risks for blood cancer may respond to COVID-19 and its emerging vaccines. 

The IMPACT study is an affiliate study of the PROMISE and PCROWD Studies. We analyze blood samples for up to one year to learn how COVID-19 exposure affects the immune system. All participants enrolled in IMPACT will receive a free antibody test to determine if they have been exposed to the virus that causes COVID-19.

The IMPACT Study is now closed and in its follow-up stage.  If you are eligible, here are two affiliate studies you can join: 

           Already enrolled? PROMISE Dashboard Login / PCROWD Dashboard Login

      Not enrolled? Both studies are welcoming new participants.

PROMISE Study Logo - Dana-Farber
IMPACT COVID-19 Study logo

1. Join as a PROMISE Study participant
The PROMISE Study is for healthy people with risks for multiple myeloma but who do not have the early warning signs (called precursor conditions.)
Who can join? 

  • Black or African American Individuals age 40 - 75 years

       – And / Or –

  • Close family members of anyone with multiple myeloma OR or a precursor condition, also 40 - 75 years of age.

Close family members are people of any race who have a parent, sibling, or child with: 

      Multiple myeloma OR one these related conditions: 

PCROWD Study Logo - Dana-Farber

2. Join as a PCROWD Study participant
For anyone, age 18+, who has been diagnosed with a precursor condition for multiple myeloma.

IMPACT Study COVID-19 Poster - Learning Together About Immune Response


  • We study how the immune system responds to COVID-19 and the long-term impact of the virus in patients with precursor conditions and healthy individuals. The goals of IMPACT are:


  • To compare COVID-19 antibody levels and immune cell changes in patients with precursor conditions to those without precursor conditions.

  • To identify the people most at risk for long-term symptoms and immune complications after infection to COVID-19.


The coronavirus disease, called COVID-19, continues to have a serious impact on millions of people, including people with or at risk for cancer. It is important to learn how COVID-19 will impact people with risks for blood cancer.

We Seek to Learn Answers to Questions Like These:

  • Do people who have risks for blood cancer also have greater risks for COVID-19?

  • If so, is there a COVID-19 treatment that would help people with cancer risks to protect their long-term health? 

  • Who is most at risk for long-term symptoms and immune complications after infection with COVID-19?

  • Will precursor conditions make future COVID-19 vaccines more or less effective?

  • Do precursor patients who have recovered from COVID-19 have COVID-19 antibodies?

  • Are these patients who have recovered from COVID-19 protected from re-infection?  If so, for how long?

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